Results
| PMID | 16045534 |
| Gene Name | IL17A |
| Condition | Endometriosis |
| Association |
Associated |
| Sex | Female |
| Infertility type | Female infertility |
| Other associated phenotypes |
Endometriosis, Female infertility, Endometriosis associated infertility |
|
BJOG. 2005 Aug;112(8):1153-5. Zhang, Xinmei| Xu, Hong| Lin, Jun| Qian, Yuli| Deng, Lin Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People's Republic of China. This prospective study aimed to determine whether patients with endometriosis are having different level of interlukin-17 (IL-17) in peritoneal fluid when compared with patients without endometriosis. The patients with minimal/mild endometriosis had a significantly higher level of IL-17 in peritoneal fluid compared with those with moderate/severe endometriosis or without endometriosis. The concentration of IL-17 in peritoneal fluid was significantly higher when endometriosis and infertility coexist. However, the concentration of IL-17 in peritoneal fluid did not correlate with the phase of the menstrual cycle in the patients with or without endometriosis. Our study suggested that IL-17 might play an important role in the pathogenesis of early endometriosis and endometriosis-associated infertility. Mesh Terms: Abdominal Pain/etiology| Adult| Ascitic Fluid/*chemistry| Case-Control Studies| Endometriosis/*etiology/metabolism| Female| Humans| Infertility, Female/*etiology/metabolism| Interleukin-17/*metabolism| Menstrual Cycle/physiology| Prospective Stu |
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